Digestive Health Institute

by Dr. Muffi

Digestive Health Institute

by Dr. Muffi

Small Intestine Cancer

Info | Symptoms | Diagnosis | Treatment Options

What You Need to Know

Small intestine cancer (also called small bowel cancer) develops when abnormal cells grow uncontrollably in the lining of the small intestine. Because it is rare and can mimic other digestive issues, diagnosis is often delayed. Early detection and treatment improve chances of recovery.

Common Symptoms of Small Intestine Cancer

If you notice any of the following, speak with your doctor:

  • Abdominal pain or cramping
  • Unexplained weight loss
  • Nausea or vomiting
  • Blood in stool
  • Fatigue or weakness
  • Blockage symptoms (severe pain, bloating, inability to pass stool or gas)

Diagnosis & Evaluation

  • Endoscopy / Enteroscopy (camera examination of the small intestine)
  • Imaging scans (CT, MRI, PET)
  • Biopsy (to confirm cancer cells)
  • Blood tests (including anemia screening and tumor markers)

Treatment Options

Treatment depends on the location, type, and stage of the tumor. A personalized care plan may include:

  1. Segmental Resection (Small Bowel Resection)
    Removal of the cancerous section of the small intestine with a margin of healthy tissue, followed by reconnection (anastomosis).
  2. Whipple Procedure (Pancreaticoduodenectomy)
    Used for tumors in the duodenum, especially near the pancreas. Involves removal of part of the pancreas, duodenum, and surrounding structures.
  3. Laparoscopic or Robotic Resection
    Minimally invasive options for selected cases, offering quicker recovery and smaller incisions.
  4. Debulking Surgery
    For advanced disease where complete removal isn’t possible, surgeons reduce tumor size to relieve symptoms.

Other Treatments

  • Chemotherapy: Used in advanced or recurrent disease.
  • Targeted Therapy / Immunotherapy: For specific tumor types and genetic profiles.
  • Radiation Therapy: Rarely used but may help in symptom control.
  • Surgery Duration: Typically 1 to 3 hours
  • Hospital Stay: Usually 2-3 days
  • Recovery: Most patients resume normal activities such as climbing stairs, returning to work, and driving within 1 to 2 weeks

Often yes. Treatment can affect digestion and absorption, so dietitians can help plan meals, supplements, or tube feeding if needed.

  •   Quit smoking and limit alcohol
  •   Maintain a healthy weight
  •   Eat a balanced diet
  •   Stay physically active
  •  Follow up regularly with your healthcare team

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